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𝐒𝐢𝐫𝐢𝐮𝐬𝐗𝐓 𝐢𝐬 𝐩𝐥𝐞𝐚𝐬𝐞𝐝 𝐭𝐨 𝐬𝐡𝐚𝐫𝐞 𝐬𝐨𝐦𝐞 𝐈𝐦𝐚𝐠𝐢𝐧𝐠 𝐈𝐧𝐬𝐢𝐠𝐡𝐭𝐬 𝐭𝐡𝐚𝐭 𝐦𝐚𝐲 𝐛𝐞 𝐨𝐟 𝐢𝐧𝐭𝐞𝐫𝐞𝐬𝐭 𝐭𝐨 𝐲𝐨𝐮. We plan to make Imaging Insights a regular post providing

We are excited to announce that SiriusXT is coming to the Massachusetts Institute of Technology to present its table-top Soft X-ray microscope, SXT-100. Dr Kenneth

𝐒𝐢𝐫𝐢𝐮𝐬𝐗𝐓 𝐢𝐬 𝐩𝐥𝐞𝐚𝐬𝐞𝐝 𝐭𝐨 𝐬𝐡𝐚𝐫𝐞 𝐬𝐨𝐦𝐞 𝐈𝐦𝐚𝐠𝐢𝐧𝐠 𝐈𝐧𝐬𝐢𝐠𝐡𝐭𝐬 𝐭𝐡𝐚𝐭 𝐦𝐚𝐲 𝐛𝐞 𝐨𝐟 𝐢𝐧𝐭𝐞𝐫𝐞𝐬𝐭 𝐭𝐨 𝐲𝐨𝐮. We plan to make Imaging Insights a regular post providing

Conway Imaging Core at University College Dublin (UCD) has welcomed its latest addition – the Table Top Soft X-ray Microscope. The microscope is set to

SiriusXT marks a significant milestone with the first deployment of the SXT100 Soft X-Ray microscope at Conway Imaging Institute, UCD, Dublin. SiriusXT’s SXT-100 is the

On this World Alzheimer’s Day (21st September 2023), we would like to reflect on the advancements achieved in understanding Alzheimer’s disease, as well as the

Mitochondrial disease, though once considered rare, now affects approximately 1 in 5,000 individuals, positioning it as the second most frequently diagnosed serious genetic ailment after

A new University College Dublin (UCD) led pan-European research project using correlative multimodal imaging (CMI) to improve the understanding of biomedical processes of disease and

SiriusXT, a pioneer in Laboratory Soft X-ray Microscopy, is proud to announce its plans to participate in two leading microscopy conferences in July 2023. These

SiriusXT’s SXT-100 Soft X-ray Microscope images with a wide field-of-view that offers a unique means of imaging inter- and intracellular structure of closely packed cells,

Daffodil Day is an annual fundraising event held in many countries to raise awareness and funds for cancer research and support services. The day typically

Soft X-ray tomography (SXT) is a powerful microscopy technique for studying three-dimensional (3D) structures in biological and materials research. Off-line fluorescence microscopy (FM) is often

Imaging the whole internal structure of intact biological cells at nanometre-resolution, by first acquiring a +/- 65 degree tilt series with one-degree tilt increments and

On 27th January 2023, Kenneth Fahy (VP of Product Management, SiriusXT) spoke in the latest episode of the Euro-BioImaging Tech Exchange webinar series. This was

World Cancer Day is observed worldwide on February 4. The aim is to inform and encourage people on its prevention, early detection, and treatment. Cancer

Hydroxyapatite (HA) in the form of nanoparticles (NPs) is widely used as a vehicle for the transport of genetic material into cells and in bone

As we approach the end of 2022, the soft X-ray microscopy community can look back on a year of continued growth in the use of

Gold nanoparticles have important diagnostic and therapeutic uses. Furthermore, they have recently been found to act as potent antimicrobial agents. Soft X-ray tomography (SXT) was

The global diabetes prevalence in 20 to 79 year olds in 2021 was estimated at over 530 million people, giving rise to healthcare costs of

National Herpes Awareness Day, celebrated on October 13, is a chance to promote awareness about the causes, dangers, and treatment of many forms of herpes

It was great to see the premier microscopy event of 2022 taking place again as an in-person event at the beautiful Oregon Convention Center in

Cryo soft X-ray tomography using low-energy X-rays is a powerful method for imaging the 3D ultrastructure of whole cells to around 50 nm resolution. Cells

Virosomes, which are like non-replicating “artificial viruses,” are capable of delivering vaccination antigens to targeted sites in a host cell. In general, a virosome is

The 19th of June has been designated as World Sickle Cell Awareness Day, the purpose of which is to enhance public education and understanding of

Glioblastoma multiforme (GBM) is a fast-growing glioma brain tumour arising from brain cells, called glial cells, and is the most common type of primary malignant

Cryo-soft X-ray tomography (cryo-SXT) is an emerging imaging technology that solves the demand for imaging the whole ultrastructure of relatively thick cell samples without staining

Cell adhesion is the process by which cells interact with and connect to neighbouring cells via specialized cell surface chemicals. This process can take place

On May 9th and 10th members of the CoCID consortium convened at the Alba synchrotron for the second, in-person, CoCID meeting. Twenty participants with representatives

World Asthma Day is an annual event hosted by the Global Initiative for Asthma to raise asthma awareness and care across the world. The theme

World Malaria Day is an annual event observed on April 25 to promote awareness of the global effort to control and eventually eradicate malaria. According

Every year on April 19, World Liver Day is celebrated with the goal of raising liver health awareness and also of drawing attention to liver

A recently-reported study, conducted by researchers from the Harvard T.H. Chan School of Public Health and published in the US National Institute of Health’s Research

The most appropriate cell imaging modality for a given bioimaging application is a trade-off between the deliverables associated with the optical setup of the microscope

Soft x-ray tomography is an ideal imaging modality for characterizing organelle assembly within a biological cell, which informs the disease researcher about cellular mechanisms in

Daffodil Day is an annual campaign that raises life-saving funds for world-class cancer research. It helps highlight the immense pain and economic cost that cancer

Soft X-ray Tomography (SXT) is an ideal imaging modality for mapping the interaction of organelle within biological cells, given its ability to image the whole

This paper from the Advanced Light Source, LBNL, presents a detailed step by step protocol for full rotation soft X-ray tomography (SXT) of single cells.

Mitochondria are membrane-bound cell organelles that generate most of the chemical energy needed to power the cell’s biochemical reactions. Mitochondria form a dynamic and interconnected

Hepatitis C virus (HCV) is an enveloped RNA virus. One of the hallmarks of HCV infection is a rearrangement of the host cell membranes, known

Nanoparticles are increasingly being used to improve the bioavailability of a range of drugs, vaccines, adjuvants etc. to targeted sites within a cell. Targeting a

2021 saw a significant increase in nanomedicine research and, in particular, in the use of nanoparticles as transport carriers for the precise delivery of vaccines,

The paper below does a great job of elucidating the benefits of correlating soft x-ray tomography with super-resolution fluorescence microscopy in order to image the

The analysis of 3D architecture of infected cells is critical for understanding the mechanisms of viral diseases. Soft X-ray tomography (SXT) is a technology that

Viruses are obligate parasites that depend on a host cell for replication and survival. Consequently, to fully understand the viral processes involved in infection and

Monday, October 27th, 2021, was the day that many of the CoCID team members had been looking forward to. The day when team members from

2021 marks the 100-year anniversary of the discovery of Insulin as a treatment for Diabetes. In 1921, Sir Frederick G Banting and Charles H Best,

” The challenge in understanding the complex spatial systems of entire organs and tumours will only be met by designing new multimodal and correlative workflows

”The SXM microscope developed by SiriusXT performs just as well but is many times smaller, less expensive, and still very fast.” – Dr Venera Weinhardt,

The European Light Microscopy Initiative 2021 (elmi2021) conference took place virtually this year, between June 22nd and 25th. SiriusXT was pleased with the interest received in

”Viral diseases are not only an important cause of mortality, they also carry a significant social and economic cost to humanity.  An analysis of three-dimensional