-
UCD spin-out SiriusXT was set up with the intention of ‘revolutionising cell and tissue imaging’ via a lab-based soft x-ray microscope.

Chck out the article on SiriusXT in siliconrepublic Advancing medicine and human healthcare is something that has always be at the forefront of society – and in this increasingly technological age, this sentiment shows no sign of stopping. In fact, according to an analysis from Fortune Business Insights, the medical devices market size was valued at more…
-
Announcing Our New Website: SiriusXT.com

Across-scales imaging is easy to promise and hard to deliver. Core Imaging Labs are being asked for three things at once; native-state preservation, context-rich views of real biology, and increased throughput. Add the need to correlate with EM (cryo-We are delighted to announce the launch of our new SiriusXT website. We would like to explain…
-
From Promise to Practice: Making Across-Scales Imaging Work

Across-scales imaging is easy to promise and hard to deliver. Core Imaging Labs are being asked for three things at once; native-state preservation, context-rich views of real biology, and increased throughput. Add the need to correlate with EM (cryo-FIB/cryo-ET), FM and sometimes chemistry-aware tools (SIMS, Raman), and the result is too often contaminated samples, long…
-
Bridging the Gaps in Cryo-Imaging Workflows:

How the SXT-100 Empowers Core Imaging Labs Core Imaging Lab Managers face mounting pressure to deliver faster, higher-quality cryo-imaging results to their internal customers while adapting to a rapidly evolving set of scientific demands. As structural biology moves beyond isolated molecules toward “imaging across scales” – from tissue and organoid models down to molecular detail…
-
Join researchers from across the UK for an event filled with insightful talks, networking opportunities, and the latest in cryo microscopy!

At the Vienna Region Cryo-EM Seminar on April 23rd, Dr. Kathrin Rudolph, Regional Market Specialist for Life Science products at TESCAN, presented the compelling results of a collaborative study titled: “A cryo-workflow combining light, electron and soft X-ray microscopy provides targeting of unlabelled features.” Kathrin’s presentation highlighted how Soft X-ray Microscopy (SXM) is emerging as…
-
Unlocking Nanoscale Insights with a Novel Cryo-Imahing Workflow!

At the Vienna Region Cryo-EM Seminar on April 23rd, Dr. Kathrin Rudolph, Regional Market Specialist for Life Science products at TESCAN, presented the compelling results of a collaborative study titled: “A cryo-workflow combining light, electron and soft X-ray microscopy provides targeting of unlabelled features.” Kathrin’s presentation highlighted how Soft X-ray Microscopy (SXM) is emerging as…
-
Soft X-ray Tomography Has Evolved into a Powerful Tool for Revealing Cell Structures!

A new review in the Annual Review of Analytical Chemistry by Venera Weinhardt and Carolyn Larabell charts the evolution of soft X-ray tomography (SXT) from its synchrotron-based roots to today’s lab-scale systems. SiriusXT is proud to see our SXT-100 microscope featured, highlighting SXT’s transformation into a high-throughput, quantitative technique for imaging intact, fully hydrated cells…
-
Award winning discoveries made possible with Soft X-ray Microscopy!!!

Every year since 1923 the American Association for the Advancement of Science (AAAS) awards the Newcomb Cleveland Prize to the authors of an outstanding research article published in the prestigious ‘Science’ peer-reviewed academic journal. The 2025 AAAS Newcomb Cleveland Prize was awarded to an international team of researchers for their extraordinary research entitled “Nitrogen-fixing organelle…
-
Professor Gerd Schneider, Head of Microscopy at Halmholtz Zentrum Berlin, will be holding a seminar taking place in University College Dublin on Friday 21st March!

Professor Schneider is one of the early pioneers of Soft X-ray Tomography, thus it is an honor to have him host a seminar in UCD, where the world’s first commercial laboratory-based soft X-ray microscope, SiriusXT’s SXT-100, has been commissioned! Professor Schneider’s seminar will cover the topic of “Nanoscale X-ray imaging and spectromicroscopy with synchrotron radiation”…
-
Soft X-ray tomography – providing precision targeting of regions of interest in correlative imaging workflows!

Dr Kenneth Fahy, SiriusXT, presented at the EMBO workshop that took place in EMBL, covering the topic “Cryo Soft X-ray Tomography for efficient targeting and volume context in CLEM and Volume EM correlative workflows”. Soft X-ray tomography (SXT) is a powerful standalone imaging technique with the unique capability to non-destructively image the whole 3D subcellular…